Do you consider stitching knots with dread? If so you aren’t alone. I know many stitchers who avoid knots or who do not feel comfortable stitching them.
Mary Corbet, Needle n’Thread, wants you to think about using them more often. To this end she has a blog post with 12 knots and knot-like stitches.
Remember these stitches are done of fabric, not canvas. In needlepoint, the stitches are made the same way, just using the holes in the canvas.